Catalytic CO₂ hydrogenation to CH₄ provides a promising approach to producing natural gas, and reducing the emissions of global CO₂. However, the efficiency of catalytic CO₂ methanation is limited by slow kinetics at low temperatures. This study first demonstrates that an air- and water-stable perovskite oxyhydride BaTiO_2.4H_0.6 could function as an active support material for Ni-, Ru-based catalysts for CO₂ methanation at 300–350 °C, a relatively lower temperature. With the oxyhydride support, the activity for Ni and Ru increases by a factor of 2–7 when compared to the BaTiO₃ oxide support. Kinetic analysis shows reduced H₂ poisoning probably due to spillover, implying that the activity change is due to the kinetics being influenced by hydride. Furthermore, the oxyhydride-supported Ni catalyst is also durable with its catalytic performance preserved for at least 10 h under a humid environment at elevated temperatures. It is anticipated that these perovskite oxyhydrides will shed new light on the design of high-efficiency metal-based catalysts for water-involved catalytic reactions.